Image shows a metaphase spread revealing the 46 human chromosomes (blue). Telomeres have been labeled using PNA-FISH and appear as pale dots at the ends of each chromatid.
Biological Process: Chromosome organization, Mitosis, Mitotic metaphase
See E. Michishita et al. 2008. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452:492-496.
Author: Thomas Ried
Source: The Cell: An Image Library
