Extensive Tissue Necrosis of the Lower Limb in an 11-Year-Old Boy who had been bitten two weeks earlier by a Bothrops asper (viper) in Ecuador. The degree of necrosis is sufficiently severe that some form of surgical amputation above the knee would have been inevitable.Author: D. A. WarrellSource: Gutiérrez JM, Theakston RDG, Warrell DA (2006) Confronting the Neglected Problem of Snake Bite Envenoming: The Need for a Global Partnership. PLoS Med 3(6): e150