Oligonucleotides (or oligos) are short, single-stranded DNA or RNA molecules. Oligos have a wide range of applications in biochemistry, biology, molecular diagnostics, genomics, and other molecular biology experiments. Oligos may be unmodified or modified with a variety of chemical moieties depending on their intended use, for example, the addition of 5' or 3' phosphate groups to enable ligation or block extension, respectively, labeling with radionuclides or fluorophores and/or quenchers for use as probes, the incorporation of thiol, amino, or other reactive moieties to enable the covalent coupling of functional molecules such as enzymes, and extension with other linkers and spacers of diverse functionality.
Creative Biogene is a leading biotechnology company that has the expertise and ability in providing oligonucleotide synthesis services for customers worldwide. Creative Biogene's sophisticated types of equipment, advanced technologies, and highly experienced staff are available to provide clients a full spectrum of high-quality specialty oligonucleotide synthesis services ranging from oligo synthesis for research and GMP grade, modified oligonucleotides to high throughput DNA or RNA oligo synthesis.