Fungi are a large and diverse species of eukaryotes. There are currently more than 100,000 known species. Since the Saccharomyces cerevisiae genome was obtained in 1996, more and more fungal genomes have been analyzed and published. Fungal DNA sequences with unknown functions inspire efforts in the identification of these genes and their biological characteristics, which have become a research hotspot in the post-genomic era.
Creative Biogene can use CRISPR/Cas9 gene editing, T-DNA insertion, homologous recombination, RNA interference and other technologies to assist scientific researchers in exploring gene functions and modifying fungal genomes. Various fungi have differences in the efficiencies of transformation, expression systems, and gene editing. After years of technology accumulation, transformation and genome modification have been successfully achieved in fungi, such as yeasts (e.g. Pichia pastoris, Saccharomyces cerevisiae), Candida albicans, Talaromyces marneffei, Monascus, Aspergillus niger, Penicillium, Rhizopus, Mucor. We can also provide customized genome editing services for other fungi according to clients' requirements.
