Microbial fermentation is the basis of pharmaceuticals, and the application of fermentation in pharmaceuticals mainly refers to the process of using the growth and reproduction of microorganisms to synthesize active molecules through metabolism, biotransformation, and then separation and extraction, and refinement and purification. The microorganisms that produce drugs mainly include bacteria, actinomycetes and filamentous fungi, as well as Pseudomonas, Bacillus, Mucor, Cyanobacteria, etc. With the development of biotechnology, especially the rise of biotechnology such as genome sequencing, genetic engineering, protein engineering and metabolic engineering, there is still a broad prospect of obtaining new natural products from microorganisms.
