Alzheimer's Disease Model

Alzheimer's Disease ModelMouse models are one of the most important research tools in the search for new therapies for Alzheimer's disease.

Mice are highly phylogenetically protected from humans in the structure and function of hippocampal and internal olfactory cortex circuits that mediate episodic memory and are vulnerable to Alzheimer's disease.

Mice have a similar number of genes and a considerable amount of chromosomal homology to humans.

The mouse model provides a sufficiently simplified system to facilitate experimental manipulation.

Mouse models of Alzheimer's disease are useful as a tool for target identification and validation.