An aspergilloma is understood as the local settling and foreclosure of a mold fungus (mostly Aspergillus fumigatus) in existing physical or pathological hollow spaces (eg. cysts, tubercoulous caverns). The aspired mold spores preferably infest the paranasal sinuses or the pathological hollow spaces of the lung tissue.Solitary aspergilloma of the lung mostly show a progression with few complaints which may be accompanied by dyspnoic complaints depending on the size of the aspergilloma. When the caverns disrupt into the bronchial systems hemoptyses will occur.
In a generalized infestation of the lung tissue (pulmonary aspergillosis), the symptoms can be associated to an allergic bronchio-pulmonary aspergillosis or an aspergillus pneumonia.
Diagnostics is taken by imaging techniques (CT, MRI). Therapy includes surgical excision of the nodule.
Histopathology of Aspergilloma. H&E staining. Magnification 200xAuthor: Marvin 101