Not real polyposis in Crohn's disease, but "cobblestone phenomenon": Sections of inflamed mucosa alternate with deep ulcerations, thus generating the impression of cobblestones.Crohn's disease belongs to a group of chronic inflammatory bowel disease. It is a chronic granulomatous inflammation, which may occur in the whole gastrointestinal tract, from mouth to anus. In most cases the lower small intestine (terminal ileum involvement in about 40%) and colon (colon) are involved, rarely esophagus (esophageal) and mouth are involved, too. A characteristic feature of Crohn's disease is discontinuous, segmental involvement (so-called "skip lesions") of the intestinal mucosa, separated by healthy portions of mucosa.
