Chromophobic renal cell carcinoma - as in histology, there are two different cell populations in cytology. Next to plant cell like large, bright cells one can also see groups of small cubic cells with a denser cytoplasm and a little smaller nuclei. The margins of the cells are remarkeably sharp. Clinical history: 78 year old male patient with kidney tumor Stain: PapanicolaouSource: ©PathoPic