Invasive ductal carcinoma of the breast: lymph node metastasis - basically all nuclei of the tumor demonstrate strong positivity for estrogen receptor.Clinical presentation: 71-year-old patient; status post breast cancer and colon cancer. Presents with enlarged supraclavicular lymph nodes.Comment: The positivity for these hormone receptors indicates metastatic breast cancer.Immunohistochemistry: estrogen receptor.Source: ©PathoPic